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biopax3:comment |
Authored: Garapati, P V, 2010-08-02,
Edited: Garapati, P V, 2010-08-02,
IPS-1/MAVS/Cardif/VISA with its TRAF-interaction motif (TIM) directly interacts with TRAF3 and recruits TRAF3 to the RIG-I/MDA5 signaling complex. TRAF3 acts as a scaffold for the assembly of a signaling complex composed of IKK epsilon/TBK1, leading to the activation of transcription factors IRF3/IRF7.,
Reviewed: Kawai, T, Akira, S, 2010-10-30
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