Source:http://www.reactome.org/biopax/48887BiochemicalReaction2685
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Authored: Garapati, P V, 2010-08-02,
Edited: Garapati, P V, 2010-08-02,
Phosphorylation of these transcription factors IRF3 and IRF7 results in a conformational change that allows their dimerization to form homo- or hetero dimers. Each of the three different combinations of dimers (IRF3:IRF3, IRF7:IRF7 and IRF3:IRF7) may selectively effect the transcription of IFN-alpha gene subfamilies and IFN-beta genes.,
Reviewed: Kawai, T, Akira, S, 2010-10-30
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Dimerization of Phospho IRF3 or phospho IRF7
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