rdf:type |
|
lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0033371,
umls-concept:C0040691,
umls-concept:C0123256,
umls-concept:C0185117,
umls-concept:C0599946,
umls-concept:C1516859,
umls-concept:C1527194,
umls-concept:C1704259,
umls-concept:C1705987,
umls-concept:C2911684
|
pubmed:issue |
9
|
pubmed:dateCreated |
2010-10-4
|
pubmed:abstractText |
Decidualization (differentiation) of the endometrial stromal cells during the secretory phase of the menstrual cycle is essential for successful implantation. Transforming Growth Factor ?1 (TGF?1) canonically propagates its actions via SMAD signalling. A role for TGF?1 in decidualization remains to be established and published data concerning effects of TGF?1 on markers of endometrial decidualization are inconsistent.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
1932-6203
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
5
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
e12970
|
pubmed:dateRevised |
2011-8-19
|
pubmed:meshHeading |
pubmed-meshheading:20885978-Cell Differentiation,
pubmed-meshheading:20885978-Cells, Cultured,
pubmed-meshheading:20885978-Down-Regulation,
pubmed-meshheading:20885978-Endometrium,
pubmed-meshheading:20885978-Female,
pubmed-meshheading:20885978-Gene Expression Regulation,
pubmed-meshheading:20885978-Humans,
pubmed-meshheading:20885978-Insulin-Like Growth Factor Binding Protein 1,
pubmed-meshheading:20885978-Pregnancy,
pubmed-meshheading:20885978-Prolactin,
pubmed-meshheading:20885978-Signal Transduction,
pubmed-meshheading:20885978-Smad4 Protein,
pubmed-meshheading:20885978-Stromal Cells,
pubmed-meshheading:20885978-Transforming Growth Factor beta1
|
pubmed:year |
2010
|
pubmed:articleTitle |
TGF?1 attenuates expression of prolactin and IGFBP-1 in decidualized endometrial stromal cells by both SMAD-dependent and SMAD-independent pathways.
|
pubmed:affiliation |
Medical Research Council Human Reproductive Sciences Unit, Centre for Reproductive Biology, Queen's Medical Research Institute, Edinburgh, Scotland, United Kingdom.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|