Source:http://linkedlifedata.com/resource/umls/id/C0123256
NCI: Insulin-like growth factor binding protein 1 (259 aa, 28 kD) is a cell communication protein that is encoded by the human IGFBP1 gene and has a role in signal transduction.,MSH: One of the six homologous proteins that specifically bind insulin-like growth factors (SOMATOMEDINS) and modulate their mitogenic and metabolic actions. The function of this protein is not completely defined. However, several studies demonstrate that it inhibits IGF binding to cell surface receptors and thereby inhibits IGF-mediated mitogenic and cell metabolic actions. (Proc Soc Exp Biol Med 1993;204(1):4-29)