Transforming Growth Factors

Source:http://linkedlifedata.com/resource/umls/id/C0040691

MSH: Hormonally active polypeptides that can induce the transformed phenotype when added to normal, non-transformed cells. They have been found in culture fluids from retrovirally transformed cells and in tumor-derived cells as well as in non-neoplastic sources. Their transforming activities are due to the simultaneous action of two otherwise unrelated factors, TRANSFORMING GROWTH FACTOR ALPHA and TRANSFORMING GROWTH FACTOR BETA.,CSP: any of several proteins secreted by transformed cells and stimulating growth of normal cells; transforming growth factor alpha binds the epidermal growth factor receptor and also stimulates growth of microvascular endothelial cells; transforming growth factor beta exists as several subtypes; all occur in hematopoietic tissue, stimulate wound healing, and in vitro are antagonists of lymphopoiesis and myelopoiesis.,NCI: Transforming Growth Factors are a family of extracellular signaling peptides involved in cell growth stimulation. Found in hematopoietic tissue, various TGF-beta s

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