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biopax3:comment |
Authored: Jassal, B, 2009-04-02 10:56:26,
Edited: Jassal, B, 2009-04-02 10:56:26,
Fatty acid cyclo-oxygenase (COX) converts arachidonic acid to prostaglandin H2 (PGH2) from which the prostanoids PGD2, PGE2, PGF2alpha, PGI2 (prostacyclin) and thromboxane A2 (TXA2) are derived. Based on the agonist potencies, five prostanoid receptors are recognized and correspondingly named DP, EP, FP, IP and TP receptors (Coleman RA et al, 1994). Additionally, EP receptors contains four subtypes, termed EP1, EP2, EP3 and EP4; the DP receptor also has two subtypes, DP1 and DP2 (CRTH2).,
Reviewed: D'Eustachio, P, 2009-05-29 07:44:22
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