Source:http://www.reactome.org/biopax/48887BiochemicalReaction3425
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Authored: Jassal, B, 2009-04-02 10:56:26,
Edited: Jassal, B, 2009-04-02 10:56:26,
Once activated by PGE2, the EP2 (Regan JW et al, 1994) receptor:ligand complex can mediate downstream effects by coupling to the G protein alpha s subunit and activate adenylyl cyclase (Schwaner I et al, 1995). EP4 receptors (Bastien L et al, 1994) are present on smooth muscle cells and their effects are mediated via coupling to G protein alpha s subunit and subsequent stimulation of adenylate cyclase (Wilson RJ et al, 2004).,
Reviewed: D'Eustachio, P, 2009-05-29 07:44:22
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EP2 and EP4 receptors can bind PGE2
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