Source:http://linkedlifedata.com/resource/geneontology/id/GO:0097191
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered." [GOC:mtg_apoptosis, GOC:yaf, PMID:17340152]
|
| skos:inScheme | |
| skos:prefLabel |
extrinsic apoptotic signaling pathway
|
| skos:altLabel |
extrinsic apoptotic pathway,
extrinsic apoptotic signalling pathway
|
| skos:note |
Fas acts as a death receptor with a role in apoptosis, but can also act as a non-apoptotic signal transducer.
|
| skos:broader | |
| skos:narrowSynonym |
death receptor-mediated apoptosis,
extrinsic apoptosis,
extrinsic apoptotic signaling pathway in presence of ligand
|