Source:http://linkedlifedata.com/resource/geneontology/id/GO:0097190
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"A series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered." [GOC:mtg_apoptosis]
|
| skos:inScheme | |
| skos:prefLabel |
apoptotic signaling pathway
|
| skos:altLabel |
apoptotic signalling pathway,
induction of apoptosis by extracellular signals
|
| skos:notation |
Reactome:REACT_101039 "Ceramide signalling, Canis familiaris",
Reactome:REACT_101287 "Death Receptor Signalling, Xenopus tropicalis",
Reactome:REACT_101722 "FasL/ CD95L signaling, Rattus norvegicus",
Reactome:REACT_102105 "FASL binds FAS Receptor, Taeniopygia guttata",
Reactome:REACT_102682 "Ceramide signalling, Bos taurus",
Reactome:REACT_103565 "Death Receptor Signalling, Danio rerio",
Reactome:REACT_104430 "Ceramide signalling, Gallus gallus",
Reactome:REACT_104446 "Death Receptor Signalling, Bos taurus",
Reactome:REACT_104880 "Cell death signalling via NRAGE, NRIF and NADE, Drosophila melanogaster",
Reactome:REACT_105789 "Cell death signalling via NRAGE, NRIF and NADE, Canis familiaris",
Reactome:REACT_1059 "Extrinsic Pathway for Apoptosis, Homo sapiens",
Reactome:REACT_106019 "Ceramide signalling, Caenorhabditis elegans",
Reactome:REACT_106417 "Cell death signalling via NRAGE, NRIF and NADE, Oryza sativa",
Reactome:REACT_107145 "FASL binds FAS Receptor, Rattus norvegicus",
Reactome:REACT_107277 "Cell death signalling via NRAGE, NRIF and NADE, Rattus norvegicus",
Reactome:REACT_108226 "Ceramide signalling, Rattus norvegicus",
Reactome:REACT_108738 "FASL binds FAS Receptor, Canis familiaris",
Reactome:REACT_108954 "Cell death signalling via NRAGE, NRIF and NADE, Sus scrofa",
Reactome:REACT_110327 "FASL binds FAS Receptor, Gallus gallus",
Reactome:REACT_110777 "Extrinsic Pathway for Apoptosis, Canis familiaris",
Reactome:REACT_113012 "Extrinsic Pathway for Apoptosis, Caenorhabditis elegans",
Reactome:REACT_113720 "FasL/ CD95L signaling, Xenopus tropicalis",
Reactome:REACT_114928 "Cell death signalling via NRAGE, NRIF and NADE, Dictyostelium discoideum",
Reactome:REACT_115331 "FASL binds FAS Receptor, Xenopus tropicalis",
Reactome:REACT_13720 "Cell death signalling via NRAGE, NRIF and NADE, Homo sapiens",
Reactome:REACT_13806 "Ceramide signalling, Homo sapiens",
Reactome:REACT_1426 "FASL binds FAS Receptor, Homo sapiens",
Reactome:REACT_1619 "Death Receptor Signalling, Homo sapiens",
Reactome:REACT_28136 "Death Receptor Signalling, Taeniopygia guttata",
Reactome:REACT_30777 "Death Receptor Signalling, Sus scrofa",
Reactome:REACT_32035 "FasL/ CD95L signaling, Danio rerio",
Reactome:REACT_33023 "Ceramide signalling, Xenopus tropicalis",
Reactome:REACT_33363 "Death Receptor Signalling, Gallus gallus",
Reactome:REACT_47012 "Death Receptor Signalling, Mus musculus",
Reactome:REACT_78512 "Ceramide signalling, Taeniopygia guttata",
Reactome:REACT_78709 "Ceramide signalling, Drosophila melanogaster",
Reactome:REACT_79738 "Extrinsic Pathway for Apoptosis, Xenopus tropicalis",
Reactome:REACT_81353 "Ceramide signalling, Mus musculus",
Reactome:REACT_81381 "FasL/ CD95L signaling, Gallus gallus",
Reactome:REACT_82611 "Cell death signalling via NRAGE, NRIF and NADE, Taeniopygia guttata",
Reactome:REACT_83750 "Extrinsic Pathway for Apoptosis, Gallus gallus",
Reactome:REACT_84151 "Extrinsic Pathway for Apoptosis, Bos taurus",
Reactome:REACT_85830 "Cell death signalling via NRAGE, NRIF and NADE, Danio rerio",
Reactome:REACT_86320 "Cell death signalling via NRAGE, NRIF and NADE, Gallus gallus",
Reactome:REACT_86807 "Death Receptor Signalling, Canis familiaris",
Reactome:REACT_88410 "Cell death signalling via NRAGE, NRIF and NADE, Schizosaccharomyces pombe",
Reactome:REACT_88562 "Ceramide signalling, Danio rerio",
Reactome:REACT_89305 "FASL binds FAS Receptor, Bos taurus",
Reactome:REACT_89421 "Cell death signalling via NRAGE, NRIF and NADE, Xenopus tropicalis",
Reactome:REACT_900 "FasL/ CD95L signaling, Homo sapiens",
Reactome:REACT_90409 "Ceramide signalling, Schizosaccharomyces pombe",
Reactome:REACT_90414 "Cell death signalling via NRAGE, NRIF and NADE, Arabidopsis thaliana",
Reactome:REACT_90980 "FasL/ CD95L signaling, Canis familiaris",
Reactome:REACT_91488 "Cell death signalling via NRAGE, NRIF and NADE, Bos taurus",
Reactome:REACT_92659 "Extrinsic Pathway for Apoptosis, Sus scrofa",
Reactome:REACT_92947 "Extrinsic Pathway for Apoptosis, Danio rerio",
Reactome:REACT_93354 "Ceramide signalling, Sus scrofa",
Reactome:REACT_93927 "Cell death signalling via NRAGE, NRIF and NADE, Caenorhabditis elegans",
Reactome:REACT_94832 "Ceramide signalling, Saccharomyces cerevisiae",
Reactome:REACT_94837 "Extrinsic Pathway for Apoptosis, Taeniopygia guttata",
Reactome:REACT_95750 "FASL binds FAS Receptor, Danio rerio",
Reactome:REACT_95777 "FasL/ CD95L signaling, Taeniopygia guttata",
Reactome:REACT_96066 "Death Receptor Signalling, Rattus norvegicus",
Reactome:REACT_96229 "Extrinsic Pathway for Apoptosis, Rattus norvegicus",
Reactome:REACT_96867 "Cell death signalling via NRAGE, NRIF and NADE, Saccharomyces cerevisiae",
Reactome:REACT_97301 "Extrinsic Pathway for Apoptosis, Mus musculus",
Reactome:REACT_98119 "Cell death signalling via NRAGE, NRIF and NADE, Mus musculus",
Reactome:REACT_98804 "FasL/ CD95L signaling, Bos taurus",
Reactome:REACT_99367 "FASL binds FAS Receptor, Mus musculus",
Reactome:REACT_99865 "FasL/ CD95L signaling, Mus musculus"
|
| skos:note |
This term can be used to annotate gene products involved in apoptotic events happening downstream of the cross-talk point between the extrinsic and intrinsic apoptotic pathways. The cross-talk starts when caspase-8 cleaves Bid and truncated Bid interacts with mitochondria. From this point on it is not possible to distinguish between extrinsic and intrinsic pathways.
|
| skos:broader |