Source:http://linkedlifedata.com/resource/geneontology/id/GO:0007166
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription." [GOC:bf, GOC:mah, GOC:pr, GOC:signaling]
|
| skos:inScheme | |
| skos:prefLabel |
cell surface receptor signaling pathway
|
| skos:altLabel |
cell surface receptor linked signal transduction,
cell surface receptor linked signaling pathway,
cell surface receptor linked signalling pathway
|
| skos:notation |
Reactome:REACT_6290 "DILP binds to Drosophila insulin receptor (DINR), Drosophila melanogaster"
|
| skos:broader |