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rdf:type |
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calbc:hasCorrelation |
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skos:exactMatch |
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skos:definition |
MSH: Proteins that catalyze the unwinding of duplex DNA during replication by binding cooperatively to single-stranded regions of DNA or to short regions of duplex DNA that are undergoing transient opening. In addition DNA helicases are DNA-dependent ATPases that harness the free energy of ATP hydrolysis to translocate of DNA strands.,CSP: nonEC; ATP-driven topoisomerase which unwinds duplex DNA immediately prior to replication or transcription.,NCI: Helicases are a class of enzymes that utilize the energy of ATP hydrolysis to promote unwinding of 1.) RNA during transcription, splicing and translation or 2.) duplex DNA during replication or repair by binding cooperatively to single-stranded regions of DNA or to short regions of duplex DNA that are undergoing transient opening.,NCI: A class of enzymes that utilizes the energy of ATP hydrolysis to unwind (unzipped) dsDNA. The enzyme participate in various of biological process including DNA replication, transcription and recombination.
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skos:inScheme |
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skos:broader |
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skos:narrower |
umls-concept:C0248587,
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umls-concept:C1447487,
umls-concept:C0294901,
umls-concept:C1448753,
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umls-concept:C0761604,
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umls-concept:C0915348
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