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rdf:type |
|
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lifeskim:mentions |
umls-concept:C0004057,
umls-concept:C0017337,
umls-concept:C0030956,
umls-concept:C0033551,
umls-concept:C0034693,
umls-concept:C0040688,
umls-concept:C0392673,
umls-concept:C1565860,
umls-concept:C1704242,
umls-concept:C1705323,
umls-concept:C1879547,
umls-concept:C1883709
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pubmed:issue |
8
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|
pubmed:dateCreated |
1998-11-6
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pubmed:abstractText |
NSAIDs, such as aspirin (ASA), cause widespread mucosal damage, but repeated ASA insults appear to induce mucosal tolerance (adaptation) to this injury. The mechanism of the gastric adaptation to the damage induced by ASA has not been fully explained.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0269-2813
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
767-77
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9726391-Animals,
pubmed-meshheading:9726391-Anti-Inflammatory Agents, Non-Steroidal,
pubmed-meshheading:9726391-Aspirin,
pubmed-meshheading:9726391-Cell Division,
pubmed-meshheading:9726391-Gastric Mucosa,
pubmed-meshheading:9726391-Gene Expression,
pubmed-meshheading:9726391-Male,
pubmed-meshheading:9726391-Peptides,
pubmed-meshheading:9726391-Prostaglandin-Endoperoxide Synthases,
pubmed-meshheading:9726391-RNA, Messenger,
pubmed-meshheading:9726391-Rats,
pubmed-meshheading:9726391-Rats, Wistar,
pubmed-meshheading:9726391-Transforming Growth Factor alpha,
pubmed-meshheading:9726391-Up-Regulation
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pubmed:year |
1998
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pubmed:articleTitle |
Activation of genes for spasmolytic peptide, transforming growth factor alpha and for cyclooxygenase (COX)-1 and COX-2 during gastric adaptation to aspirin damage in rats.
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pubmed:affiliation |
Department of Medicine I, University Erlangen-Nuremberg, Germany. mpogonow@cyf-kr.edu.pl
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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