Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
13
|
| pubmed:dateCreated |
1998-10-22
|
| pubmed:abstractText |
We have previously shown that the application of ultrasound to thin-shelled microbubbles flowing through small microvessels (<7 microm in diameter) produces vessel wall ruptures in vivo. Because many intravascular drug- and gene-delivery vehicles are limited by the endothelial barrier, we hypothesized that this phenomenon could be used to deliver drug-bearing vehicles to tissue.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Sep
|
| pubmed:issn |
0009-7322
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
29
|
| pubmed:volume |
98
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1264-7
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:9751673-Animals,
pubmed-meshheading:9751673-Colloids,
pubmed-meshheading:9751673-Drug Delivery Systems,
pubmed-meshheading:9751673-Endothelium, Vascular,
pubmed-meshheading:9751673-Erythrocytes,
pubmed-meshheading:9751673-Female,
pubmed-meshheading:9751673-Microspheres,
pubmed-meshheading:9751673-Rats,
pubmed-meshheading:9751673-Rats, Sprague-Dawley,
pubmed-meshheading:9751673-Ultrasonics
|
| pubmed:year |
1998
|
| pubmed:articleTitle |
Delivery of colloidal particles and red blood cells to tissue through microvessel ruptures created by targeted microbubble destruction with ultrasound.
|
| pubmed:affiliation |
Department of Biomedical Engineering and the Cardiovascular Division, University of Virginia, Charlottesville, VA, USA. rprice@virginia.edu
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|