rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
6
|
pubmed:dateCreated |
1994-7-28
|
pubmed:abstractText |
In an attempt to identify the factor(s) involved in the modulation of the degradative pathway of articular cartilage, we previously reported a possible imbalance between the levels of biologically active forms of metalloproteases and tissue inhibitor of metalloprotease (TIMP) in osteoarthritis (OA) cartilage.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0023-6837
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
70
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
807-15
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:8015285-Aged,
pubmed-meshheading:8015285-Antibodies, Monoclonal,
pubmed-meshheading:8015285-Arthritis, Rheumatoid,
pubmed-meshheading:8015285-Cartilage, Articular,
pubmed-meshheading:8015285-Cells, Cultured,
pubmed-meshheading:8015285-Collagenases,
pubmed-meshheading:8015285-Glycoproteins,
pubmed-meshheading:8015285-Humans,
pubmed-meshheading:8015285-Immunohistochemistry,
pubmed-meshheading:8015285-Interleukin-1,
pubmed-meshheading:8015285-Matrix Metalloproteinase 3,
pubmed-meshheading:8015285-Metalloendopeptidases,
pubmed-meshheading:8015285-Middle Aged,
pubmed-meshheading:8015285-Osteoarthritis,
pubmed-meshheading:8015285-Proteins,
pubmed-meshheading:8015285-Reference Values,
pubmed-meshheading:8015285-Tissue Inhibitor of Metalloproteinase-2,
pubmed-meshheading:8015285-Tissue Inhibitor of Metalloproteinases
|
pubmed:year |
1994
|
pubmed:articleTitle |
Excess of metalloproteases over tissue inhibitor of metalloprotease may contribute to cartilage degradation in osteoarthritis and rheumatoid arthritis.
|
pubmed:affiliation |
Rheumatic Disease Unit Research Laboratory, Notre-Dame Hospital Research Center, University of Montreal, Canada.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|