rdf:type |
|
lifeskim:mentions |
umls-concept:C0011847,
umls-concept:C0032914,
umls-concept:C0032961,
umls-concept:C0033684,
umls-concept:C0040300,
umls-concept:C0041427,
umls-concept:C0123256,
umls-concept:C0229671,
umls-concept:C0231242,
umls-concept:C0441889,
umls-concept:C1334092
|
pubmed:issue |
1
|
pubmed:dateCreated |
1985-1-15
|
pubmed:abstractText |
PP12 is one of the recently discovered soluble tissue antigens of the placenta. During normal pregnancy maternal serum PP12 levels rise during the first 18 weeks reaching a mean peak value of 139.9 +/- 40.26 micrograms/l; after that there is a fall to a mean value of 111.9 +/- 42.39 micrograms/l between 28 and 40 weeks. Significantly higher mean serum PP12 levels were found in the third trimester in two high risk pregnancy groups (281.09 +/- 117.08 micrograms/l in pre-eclamptic toxaemia and 203.71 +/- 73.77 micrograms/l in diabetes) while serum PP12 levels remained normal (114.94 +/- 58.06 micrograms/l) in twin pregnancy. The increase of serum PP12 concentration in toxaemia and in diabetes may be of considerable diagnostic significance.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0170-9925
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
236
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
41-5
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:6508361-Female,
pubmed-meshheading:6508361-Humans,
pubmed-meshheading:6508361-Insulin-Like Growth Factor Binding Protein 1,
pubmed-meshheading:6508361-Insulin-Like Growth Factor Binding Proteins,
pubmed-meshheading:6508361-Pre-Eclampsia,
pubmed-meshheading:6508361-Pregnancy,
pubmed-meshheading:6508361-Pregnancy, Multiple,
pubmed-meshheading:6508361-Pregnancy Complications,
pubmed-meshheading:6508361-Pregnancy Proteins,
pubmed-meshheading:6508361-Pregnancy Trimester, Third,
pubmed-meshheading:6508361-Pregnancy in Diabetics,
pubmed-meshheading:6508361-Radioimmunoassay,
pubmed-meshheading:6508361-Twins
|
pubmed:year |
1984
|
pubmed:articleTitle |
Serum levels of placenta-specific tissue protein 12 (PP12) in pregnancies complicated by pre-eclampsia, diabetes or twins.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|