Linked Life Data

2959525

Source:http://linkedlifedata.com/resource/pubmed/id/2959525

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1987-12-15
pubmed:abstractText
The more common Cd-saturation method for metallothionein (MT) analysis in tissues is compared with a recently developed radioimmunoassay (RIA). The Cd-saturation assay as described by others is fast, but less specific and accurate than the RIA. The former assay, previously used for MT analysis in urine and plasma, was modified to suit its use in measuring MT concentration in tissues. Liver and kidney from control rats were assayed and values of 7 and 67 micrograms/g were measured in the two tissues, respectively. The detection limit of the assay is 10 ng/g. A modified version of the Cd-saturation assay, which was limited with respect to the number of samples that can be analyzed at one time, gave results which were similar to the ones obtained by the RIA. The advantages and the problems associated with the two assays are discussed.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0071-335X
pubmed:author
pubmed:issnType
Print
pubmed:volume
52
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
343-9
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Comparison of cadmium-saturation assay and radioimmunoassay for the determination of metallothionein concentration in tissues.
pubmed:affiliation
Department of Pharmacology & Toxicology, University of Rhode Island, Kingston.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S.