|
rdf:type |
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lifeskim:mentions |
umls-concept:C0007585,
umls-concept:C0021853,
umls-concept:C0026336,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0040688,
umls-concept:C0333355,
umls-concept:C0682610,
umls-concept:C1514485,
umls-concept:C1527195,
umls-concept:C2004454
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pubmed:issue |
12
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pubmed:dateCreated |
2008-11-21
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pubmed:abstractText |
Recent evidence suggests that transforming growth factor-alpha (TGF-alpha) enhances enterocyte proliferation and exerts a gut trophic effect. The purpose of the present study was to evaluate the effect of TGF-alpha on enterocyte proliferation and intestinal recovery following methotrexate (MTX)-induced intestinal mucositis in rats and in Caco-2 cells.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0179-0358
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1303-11
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pubmed:meshHeading |
pubmed-meshheading:18956197-Animals,
pubmed-meshheading:18956197-Caco-2 Cells,
pubmed-meshheading:18956197-Cell Proliferation,
pubmed-meshheading:18956197-Disease Models, Animal,
pubmed-meshheading:18956197-Enterocytes,
pubmed-meshheading:18956197-Humans,
pubmed-meshheading:18956197-Intercellular Signaling Peptides and Proteins,
pubmed-meshheading:18956197-Intestinal Mucosa,
pubmed-meshheading:18956197-Male,
pubmed-meshheading:18956197-Methotrexate,
pubmed-meshheading:18956197-Mucositis,
pubmed-meshheading:18956197-Noxae,
pubmed-meshheading:18956197-Rats,
pubmed-meshheading:18956197-Rats, Sprague-Dawley,
pubmed-meshheading:18956197-Recovery of Function,
pubmed-meshheading:18956197-Transforming Growth Factor alpha
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|
pubmed:year |
2008
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pubmed:articleTitle |
Transforming growth factor-alpha stimulates enterocyte proliferation and accelerates intestinal recovery following methotrexate-induced intestinal mucositis in a rat and a cell culture model.
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pubmed:affiliation |
Laboratory of Intestinal Adaptation and Recovery, The Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel. igor-dr@internet-zahav.net
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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