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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2006-10-26
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pubmed:abstractText |
The proenzyme of matrix metalloproteinase 7 (proMMP-7), which can degrade various extracellular matrix (ECM) and non-ECM molecules after being activated, is overexpressed in osteoarthritic (OA) articular cartilage, but the process of its activation in the cartilage remains unknown. The present study was undertaken to investigate the expression of tetraspanin CD151 in OA cartilage and its involvement in proMMP-7 activation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD151,
http://linkedlifedata.com/resource/pubmed/chemical/CD151 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-1alpha,
http://linkedlifedata.com/resource/pubmed/chemical/MMP7 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 7,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Transforming Growth Factor beta,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha,
http://linkedlifedata.com/resource/pubmed/chemical/Vascular Endothelial Growth Factor A
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0004-3591
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
54
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3233-43
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:17009258-Aged,
pubmed-meshheading:17009258-Aged, 80 and over,
pubmed-meshheading:17009258-Antigens, CD,
pubmed-meshheading:17009258-Antigens, CD151,
pubmed-meshheading:17009258-Cartilage,
pubmed-meshheading:17009258-Cells, Cultured,
pubmed-meshheading:17009258-Chondrocytes,
pubmed-meshheading:17009258-Gene Expression Regulation,
pubmed-meshheading:17009258-Humans,
pubmed-meshheading:17009258-Interleukin-1alpha,
pubmed-meshheading:17009258-Matrix Metalloproteinase 7,
pubmed-meshheading:17009258-Middle Aged,
pubmed-meshheading:17009258-Osteoarthritis, Hip,
pubmed-meshheading:17009258-Osteoarthritis, Knee,
pubmed-meshheading:17009258-RNA, Messenger,
pubmed-meshheading:17009258-Transforming Growth Factor beta,
pubmed-meshheading:17009258-Tumor Necrosis Factor-alpha,
pubmed-meshheading:17009258-Vascular Endothelial Growth Factor A
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pubmed:year |
2006
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pubmed:articleTitle |
Tetraspanin CD151 is expressed in osteoarthritic cartilage and is involved in pericellular activation of pro-matrix metalloproteinase 7 in osteoarthritic chondrocytes.
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pubmed:affiliation |
School of Medicine, Keio University, Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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