PHEMX protein, human

Source:http://linkedlifedata.com/resource/umls/id/C1312720

NCI: Encoded by human PHEMX Gene, 320-amino acid 34.6 kD ubiquitous TSSC6 Protein (Tetraspanin Family) is an integral membrane protein of 290 amino acids that shows no similarity to any reported protein and may play a role in hematopoietic cell function. High levels of expression are confined to hematopoietic tissues including peripheral blood leukocytes, thymus, and spleen. Alterations in TSSC6 Protein or its gene may be associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, as well as lung, ovarian, and breast cancer. (from SWISS-PROT, OMIM, and NCI),CSP: cell surface proteins that span the membrane four times and are found on many different cell types in many organisms; form cell surface complexes with other molecules participating in cell adhesion, either to the extracellular matrix (ECM) or to other cells, and with molecules required for signaling; also called tetraspans or the transmembrane 4 superfamily (TM4SF).

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