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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1-2
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pubmed:dateCreated |
2006-9-4
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pubmed:abstractText |
Recent studies have suggested that connective tissue growth factor (CTGF) plays a key role in tissue fibrosis including renal scarring. While studies showed several forms of CTGF with 10-38 kDa in the body fluids, little is known about these small molecule species. We investigated the effect of a 10 kDa CTGF molecule consisting of module 4, on the epithelial mesenchymal transition (EMT) in human proximal tubular cell line (HK-2).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Actins,
http://linkedlifedata.com/resource/pubmed/chemical/CTGF protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Connective Tissue Growth Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Fibronectins,
http://linkedlifedata.com/resource/pubmed/chemical/Immediate-Early Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Intercellular Signaling Peptides...,
http://linkedlifedata.com/resource/pubmed/chemical/Keratins,
http://linkedlifedata.com/resource/pubmed/chemical/Peptide Fragments,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Vimentin
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0009-8981
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
373
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
144-50
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:16828074-Actins,
pubmed-meshheading:16828074-Cell Line,
pubmed-meshheading:16828074-Cells, Cultured,
pubmed-meshheading:16828074-Connective Tissue Growth Factor,
pubmed-meshheading:16828074-Epithelial Cells,
pubmed-meshheading:16828074-Fibronectins,
pubmed-meshheading:16828074-Humans,
pubmed-meshheading:16828074-Immediate-Early Proteins,
pubmed-meshheading:16828074-Immunohistochemistry,
pubmed-meshheading:16828074-Intercellular Signaling Peptides and Proteins,
pubmed-meshheading:16828074-Keratins,
pubmed-meshheading:16828074-Mesoderm,
pubmed-meshheading:16828074-Microscopy, Confocal,
pubmed-meshheading:16828074-Muscle, Smooth,
pubmed-meshheading:16828074-Peptide Fragments,
pubmed-meshheading:16828074-Protein Structure, Tertiary,
pubmed-meshheading:16828074-RNA, Messenger,
pubmed-meshheading:16828074-Recombinant Proteins,
pubmed-meshheading:16828074-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:16828074-Sensitivity and Specificity,
pubmed-meshheading:16828074-Signal Transduction,
pubmed-meshheading:16828074-Vimentin
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pubmed:year |
2006
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pubmed:articleTitle |
Role of connective tissue growth factor (CTGF) module 4 in regulating epithelial mesenchymal transition (EMT) in HK-2 cells.
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pubmed:affiliation |
Institute of Nephrology, Zhong Da Hospital, Southeast University, No. 87 Ding Jia Qiao Road, Nanjing 210009, China. liubc64@yahoo.com.cn
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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