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pubmed-article:16243232pubmed:abstractTextTo determine the effects of osteoarthritic (OA) subchondral osteoblasts on the metabolism of human OA chondrocytes in alginate beads.lld:pubmed
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pubmed-article:16243232pubmed:articleTitleOsteoblasts from the sclerotic subchondral bone downregulate aggrecan but upregulate metalloproteinases expression by chondrocytes. This effect is mimicked by interleukin-6, -1beta and oncostatin M pre-treated non-sclerotic osteoblasts.lld:pubmed
pubmed-article:16243232pubmed:affiliationBone and Cartilage Metabolism Research Unit, Institute of Pathology B23, University Hospital, Sart-Tilman, 4000 Liège, Belgium.lld:pubmed
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