Source:http://linkedlifedata.com/resource/pubmed/id/15951302
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
2005-6-13
|
| pubmed:abstractText |
The relative levels of cyclin D1 (CCND1) (a) and (b) transcripts were determined by real-time reverse transcription polymerase chain reaction (RT-PCR) and found to vary according to the tissue origin in both control and tumor samples. A five-fold overexpression of both isoforms was observed in 28/38 cases of mantle cell lymphoma (MCL) and of only one isoform in 10/38 MCL. No correlation was observed between expression of cyclin D1 isoforms and CCND1 genotype at position 870.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
1592-8721
|
| pubmed:author | |
| pubmed:issnType |
Electronic
|
| pubmed:volume |
90
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
854-6
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| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:15951302-Alternative Splicing,
pubmed-meshheading:15951302-Cyclin D1,
pubmed-meshheading:15951302-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:15951302-Genotype,
pubmed-meshheading:15951302-Humans,
pubmed-meshheading:15951302-Leukocytes, Mononuclear,
pubmed-meshheading:15951302-Lymphoma, Mantle-Cell,
pubmed-meshheading:15951302-Polymorphism, Genetic,
pubmed-meshheading:15951302-Protein Isoforms,
pubmed-meshheading:15951302-Reverse Transcriptase Polymerase Chain Reaction
|
| pubmed:year |
2005
|
| pubmed:articleTitle |
The relative levels of cyclin D1a and D1b alternative transcripts in mantle cell lymphoma may depend more on sample origin than on CCND1 polymorphism.
|
| pubmed:publicationType |
Letter,
Research Support, Non-U.S. Gov't
|