|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
2004-6-8
|
|
pubmed:abstractText |
Advanced glycated end products (AGE) are endogenous proteins that have formed covalent complexes with sugars by a nonenzymatic process. Being proinflammatory molecules, AGE are thought to contribute to chronic systemic and local inflammatory processes associated with pathological changes in various diseases. In patients with end-stage renal disease, AGE are believed to play a role in the progression of atherosclerosis and worsening of renal failure. In patients receiving hemodialysis, AGE are thought to contribute to the inflammatory components of the therapy, particularly in diabetic patients.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
May
|
|
pubmed:issn |
0301-0430
|
|
pubmed:author |
pubmed-author:AzamTT,
pubmed-author:BuflerPP,
pubmed-author:DinarelloC ACA,
pubmed-author:MOER ERE,
pubmed-author:NiwaTT,
pubmed-author:PischetsriederMM,
pubmed-author:ReznikovL LLL,
pubmed-author:ShaldonSS,
pubmed-author:WaksmanJJ,
pubmed-author:WermanAA,
pubmed-author:ZhangXX
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
61
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
324-36
|
|
pubmed:dateRevised |
2007-11-14
|
|
pubmed:meshHeading |
pubmed-meshheading:15182127-Adult,
pubmed-meshheading:15182127-Female,
pubmed-meshheading:15182127-Glycosylation End Products, Advanced,
pubmed-meshheading:15182127-Humans,
pubmed-meshheading:15182127-Interleukin-1,
pubmed-meshheading:15182127-Interleukin-8,
pubmed-meshheading:15182127-Leukocytes, Mononuclear,
pubmed-meshheading:15182127-Lipopolysaccharides,
pubmed-meshheading:15182127-Male,
pubmed-meshheading:15182127-Middle Aged,
pubmed-meshheading:15182127-Tumor Necrosis Factor-alpha
|
|
pubmed:year |
2004
|
|
pubmed:articleTitle |
Effect of advanced glycation end products on endotoxin-induced TNF-alpha, IL-1beta and IL-8 in human peripheral blood mononuclear cells.
|
|
pubmed:affiliation |
Department of Medicine, Division of Infectious Diseases, University of Colorado Health Sciences Center, Denver, CO 80262, USA. Leonid.Reznikov@uchsc.edu
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
