Linked Life Data

131915

Source:http://linkedlifedata.com/resource/pubmed/id/131915

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5-6
pubmed:dateCreated
1976-8-2
pubmed:abstractText
Glycosaminoglycans (GAG) from brains, intestines, livers and skin of rats were analyzed by electrophoretic and enzymatic methods. Variations in GAG distribution have been studied in rats fed on a vitamin-A-deficient diet and on a diet supplemented with an excessive quantity of vitamin A. Hypervitaminosis A resulted in a decrease in GAG isolated from connective and hepatic tissues. The incorporation of labeled sulfate into the GAG of these tissues has been studied. Hypervitaminosis A resulted in a decrease in sulfate incorporation into the GAG isolated from connective tissues. A large increase in sulfate incorporation into the GAC of the digestive tract is observed for vitamin-A-treated rats. A decrease is noted for vitamin-A-deficient rats. It was suggested that these variations in distribution and specific activity of GAG could be due to different effects of vitamin A. Vitamin A seems to be required either for the release of lysosomal enzymes or for the sulfatation and elongation of certain glucidic chains in the biosynthesis of sulfated GAG.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0029-6678
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
225-39
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
[Influence of vitamin A on the distribution of glycosaminoglycans in rat tissues].
pubmed:publicationType
Journal Article, English Abstract