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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2003-9-17
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pubmed:abstractText |
Rheumatoid arthritis (RA) is an inflammatory disease and an angiogenic disease. However, the molecular mechanisms promoting angiogenesis in RA are not clearly identified. Our objective was to study the role of an endothelium-specific receptor tyrosine kinase, Tie2, in angiogenesis of inflammatory arthritis.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/ANGPT1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Angiogenesis Inducing Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Angiopoietin-1,
http://linkedlifedata.com/resource/pubmed/chemical/Angpt1 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/NF-kappa B,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, TIE-2,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor Protein-Tyrosine Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0004-3591
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2461-71
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pubmed:dateRevised |
2011-8-3
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pubmed:meshHeading |
pubmed-meshheading:13130465-Angiogenesis Inducing Agents,
pubmed-meshheading:13130465-Angiopoietin-1,
pubmed-meshheading:13130465-Animals,
pubmed-meshheading:13130465-Arthritis, Experimental,
pubmed-meshheading:13130465-Arthritis, Rheumatoid,
pubmed-meshheading:13130465-Endothelium,
pubmed-meshheading:13130465-Humans,
pubmed-meshheading:13130465-Membrane Glycoproteins,
pubmed-meshheading:13130465-Mice,
pubmed-meshheading:13130465-Mice, Inbred DBA,
pubmed-meshheading:13130465-NF-kappa B,
pubmed-meshheading:13130465-Neovascularization, Pathologic,
pubmed-meshheading:13130465-Receptor, TIE-2,
pubmed-meshheading:13130465-Receptor Protein-Tyrosine Kinases,
pubmed-meshheading:13130465-Signal Transduction,
pubmed-meshheading:13130465-Synovial Membrane,
pubmed-meshheading:13130465-Tumor Necrosis Factor-alpha
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pubmed:year |
2003
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pubmed:articleTitle |
Tie2 receptor tyrosine kinase, a major mediator of tumor necrosis factor alpha-induced angiogenesis in rheumatoid arthritis.
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pubmed:affiliation |
Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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