Source:http://linkedlifedata.com/resource/umls/id/C0206364
MSH: A class of cellular receptors that have an intrinsic PROTEIN-TYROSINE KINASE activity.,NCI: A class of membrane receptors that contain protein tyrosine kinase activity. This enzymatic activity is integral to the function of the receptor as a signal transducer; the phosphorylation event alters the functional activity of its protein substrate.,NCI: A catalytic PROTEIN-TYROSINE KINASE domain found on the cytoplasmic beta-portion of receptors. Many growth and differentiation factor receptors contain this domain. It is critical for the signal transduction pathways required for mitogenesis, transformation, and cell differentiation. (Neuron 1992;9:383) EC 2.7.1.-.