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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2003-9-15
pubmed:abstractText
Members of the maf gene family encode basic/leucine zipper transcription factors and play important roles during cell differentiation and organogenesis in vertebrate development. In this study, we show that the maf family is evolutionarily conserved and that the Drosophila maf (Dmaf) gene is expressed in somatic gonadal cells. During embryonic development, Dmaf mRNA is detected in somatic gonadal precursor cells emerging from dorsolateral mesoderm. Relatively weak expression is also observed in subset of neuronal cells in the central nervous system. In adult flies, Dmaf is expressed in somatic gonadal cells surrounding developing oocytes and spermatocytes. These results suggest a specific function for Dmaf in gonadal development, including migration and differentiation of primordial germ cells.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1567-133X
pubmed:author
pubmed:issnType
Print
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
663-7
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Dmaf, a novel member of Maf transcription factor family is expressed in somatic gonadal cells during embryonic development and gametogenesis in Drosophila.
pubmed:affiliation
Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916-5 Takayama, Nara 630-0192, Japan.
pubmed:publicationType
Journal Article