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pubmed-article:11967150pubmed:abstractTextDuring asymmetric cell division in the Drosophila nervous system, Numb segregates into one of two daughter cells where it is required for the establishment of the correct cell fate. Numb is uniformly cortical in interphase, but in late prophase, the protein concentrates in the cortical area overlying one of two centrosomes in an actin/myosin-dependent manner. What triggers the asymmetric localization of Numb at the onset of mitosis is unclear.lld:pubmed
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pubmed-article:11967150pubmed:articleTitleDrosophila Aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis.lld:pubmed
pubmed-article:11967150pubmed:affiliationResearch Institute of Molecular Pathology (I.M.P.), Dr. Bohr Gasse 7, A-1030, Vienna, Austria.lld:pubmed
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