STK6 protein, human

Source:http://linkedlifedata.com/resource/umls/id/C0971285

NCI: Expressed in testis, skeletal muscle, thymus, and spleen by human STK6 Gene (Aurora Ser/Thr Kinase Family), 403-aa 45.8-kDa Serine/Threonine Kinase 6 is a phosphorylated cell cycle-regulated kinase localized on centrosomes in interphase cells and at spindle poles in mitosis. Cell cycle-regulated expression accumulates in G2/M and decrease rapidly thereafter. STK6 appears to be involved in cell cycle-regulated microtubule formation and/or stabilization of the spindle pole region during chromosome segregation in anaphase and telophase. STK6 defects are responsible for centrosome aberrations, including aneuploidy. (NCI)

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