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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
1999-10-27
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pubmed:abstractText |
Neutrophil gelatinase-associated lipocalin (NGAL) is a newly described neutrophil lipocalin that may bind the proinflammatory bacterial tripeptide N-formylmethionyl-leucyl-phenylalanine. In situ hybridization and immunohistochemical studies have shown a strong NGAL expression in colonocytes and neutrophils in ulcerative colitis (UC). Because NGAL is highly protease resistant, it should be ideal for in vivo fecal and dialysate studies. Our aim was to investigate the potential of NGAL as a disease activity marker in UC and to compare it with IL-8 and TNF-alpha.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0002-9270
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
94
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2923-8
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:10520846-Acute-Phase Proteins,
pubmed-meshheading:10520846-Adult,
pubmed-meshheading:10520846-Aged,
pubmed-meshheading:10520846-Biological Markers,
pubmed-meshheading:10520846-Carrier Proteins,
pubmed-meshheading:10520846-Colitis, Ulcerative,
pubmed-meshheading:10520846-Crohn Disease,
pubmed-meshheading:10520846-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:10520846-Feces,
pubmed-meshheading:10520846-Female,
pubmed-meshheading:10520846-Humans,
pubmed-meshheading:10520846-Interleukin-8,
pubmed-meshheading:10520846-Lipocalins,
pubmed-meshheading:10520846-Male,
pubmed-meshheading:10520846-Middle Aged,
pubmed-meshheading:10520846-Neutrophils,
pubmed-meshheading:10520846-Oncogene Proteins,
pubmed-meshheading:10520846-Proto-Oncogene Proteins,
pubmed-meshheading:10520846-Rectum,
pubmed-meshheading:10520846-Tumor Necrosis Factor-alpha
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pubmed:year |
1999
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pubmed:articleTitle |
Rectal dialysate and fecal concentrations of neutrophil gelatinase-associated lipocalin, interleukin-8, and tumor necrosis factor-alpha in ulcerative colitis.
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pubmed:affiliation |
Department of Medicine CF, Glostrup Hospital, University of Copenhagen, Denmark.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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