| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
Authored: Shamovsky, V, 2009-12-16,
Edited: Shamovsky, V, 2011-08-12,
NF-kappaB is sequestered in the cytoplasm in a complex with inhibitor of NF-kappaB (IkB). Almost all NF-kappaB activation pathways are mediated by IkB kinase (IKK), which phosphorylates IkB resulting in dissociation of NF-kappaB from the complex. This allows translocation of NF-kappaB to the nucleus where it regulates gene expression.,
Reviewed: Gillespie, ME, 2010-02-27
|
| biopax3:xref | |
| biopax3:dataSource | |
| biopax3:displayName |
TAK1 activates NFkB by phosphorylation and activation of IKKs complex
|
| biopax3:organism | |
| biopax3:pathwayComponent | |
| biopax3:pathwayOrder |