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biopax3:comment |
Authored: Garapati, P V, 2009-03-23 09:59:28,
Edited: Garapati, P V, 2009-03-23 10:00:38,
Reviewed: Kumanogoh, A, Kikutani, H, 2009-09-01,
Sema3A, a prototypical semaphorin, acts as a chemorepellent or a chemoattractant for axons by activating a receptor complex comprising neuropilin-1 as the ligand-binding subunit and plexin-A1 as the signal-transducing subunit. Sema3A inhibits cell migration by inhibiting integrin ligand-binding activity.
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