| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:controlType |
INHIBITION
|
| biopax3:controlled | |
| biopax3:comment |
NLRC5 competes with IPS-1 for binding to the CARD domain of RIG-I/MDA5. NLRC5 specifically recognize the CARD domains of RIG-I/MDA5 when the CARD domains become accessible after viral infection, leading to dampened activation of IRF3.
|
| biopax3:xref | |
| biopax3:controller | |
| biopax3:dataSource | |
| biopax3:displayName |
'dsRNA:RIG-I/MDA5:NLRC5 [cytosol]' negatively regulates 'RIG-I/MDA5 interacts with IPS-1'
|