Any series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58) binding to viral RNA. RIG-I detects RNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines.
| Predicate | Object |
|---|---|
| rdf:type | |
| rdfs:comment |
Any series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58) binding to viral RNA. RIG-I detects RNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines.
|
| rdfs:subClassOf | |
| rdfs:label |
DDX58 signaling pathway,
RIG-I signaling pathway,
RIG-I signalling pathway,
retinoic acid inducible gene I signaling pathway
|
| skos:exactMatch |