Any series of molecular signals generated as a consequence of a virus or viral RNA binding to a pattern recognition receptor (PRR) located in the cytoplasm. Cytosolic PRRs such as RIG-I (DDX58) and MDA-5 (IFIH1) detect RNA synthesized during active viral replication and trigger a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines.
| Predicate | Object |
|---|---|
| rdf:type | |
| rdfs:comment |
Any series of molecular signals generated as a consequence of a virus or viral RNA binding to a pattern recognition receptor (PRR) located in the cytoplasm. Cytosolic PRRs such as RIG-I (DDX58) and MDA-5 (IFIH1) detect RNA synthesized during active viral replication and trigger a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines.
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| rdfs:subClassOf | |
| rdfs:label |
RIG-I-like receptor (RLR) signaling pathway,
RIG-I/MDA5 signaling pathway,
RIG-like helicase signaling pathway,
RIG-like receptor signaling pathway,
RLH signaling pathway,
RLR signaling pathway,
cytoplasmic caspase-recruiting domain (CARD) helicase signaling pathway,
cytoplasmic pattern recognition receptor signaling pathway in response to virus,
cytoplasmic pattern recognition receptor signalling pathway in response to virus,
virus-induced cytoplasmic pattern recognition receptor signaling pathway
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| skos:exactMatch | |
| skos:narrower |