The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a defined nucleotide across from the lesion which allows DNA synthesis to continue beyond the lesion. This process can be mutagenic depending on the damaged nucleotide and the inserted nucleotide.
| Predicate | Object |
|---|---|
| rdf:type | |
| rdfs:comment |
The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a defined nucleotide across from the lesion which allows DNA synthesis to continue beyond the lesion. This process can be mutagenic depending on the damaged nucleotide and the inserted nucleotide.
|
| rdfs:subClassOf | |
| rdfs:label |
bypass DNA synthesis,
translesion synthesis
|
| skos:exactMatch | |
| skos:narrower |