Source:http://linkedlifedata.com/resource/geneontology/id/GO:0019985
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a defined nucleotide across from the lesion which allows DNA synthesis to continue beyond the lesion. This process can be mutagenic depending on the damaged nucleotide and the inserted nucleotide." [GOC:elh, PMID:10535901]
|
| skos:inScheme | |
| skos:prefLabel |
translesion synthesis
|
| skos:altLabel |
bypass DNA synthesis
|
| skos:notation |
Reactome:REACT_115598 "DNA damage bypass, Gallus gallus",
Reactome:REACT_115640 "Translesion synthesis by Pol kappa, Gallus gallus",
Reactome:REACT_115864 "Translesion synthesis by Pol eta, Gallus gallus",
Reactome:REACT_115941 "Translesion synthesis by DNA polymerases bypassing lesion on DNA template, Gallus gallus",
Reactome:REACT_116049 "RAD18 and ubiquitinated PCNA-mediated recruitment of translesion polymerases, Gallus gallus",
Reactome:REACT_116052 "Translesion synthesis by Pol zeta, Gallus gallus"
|
| skos:broader |