Source:http://linkedlifedata.com/resource/geneontology/id/GO:0070987
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| rdf:type | |
| skos:definition |
"The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions but does not causes an increase in the endogenous mutation level. For S. cerevisiae, RAD30 encodes DNA polymerase eta, which incorporates two adenines. When incorporated across a thymine-thymine dimer, it does not increase the endogenous mutation level." [GOC:elh]
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| skos:inScheme | |
| skos:prefLabel |
error-free translesion synthesis
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| skos:note |
Note that 'error-free' does not mean that literally zero errors occur during DNA synthesis, but that the error rate is low, comparable to that of DNA synthesis during replication.
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| skos:broader |