| http://www.reactome.org/bio... | rdf:type | biopax3:Pathway | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:comment | Edited: Jassal, B, 2008-05-19 12:57:01 | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:comment | Authored: Jassal, B, 2005-03-10 15:37:26 | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:comment | Xenobiotics that contain either a carboxylic group or an aromatic hydroxylamine group are possible substrates for amino acid conjugation. Xenobiotics with a <i>carboxylic group</i> conjugate with an <i>amino group</i> of amino acids such as glycine, taurine and glutamine. The <i>hydroxylamine group</i> conjugates with the <i>carboxylic group</i> of amino acids such as proline and serine. The amino acid is first activated by an aminoacyl-tRNA-synthetase which then reacts with the hydroxylamine group to form a reactive N-ester. N-esters can degrade to form electrophilic nitrenium (R-N<sup>+</sup>-R') and carbonium (R-C<sup>+</sup>H<sub>2</sub>) ions. The pyrolysis product of tryptophan, an N-hydroxy intermediate, can potentially form these reactive electrophilic ions. | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:xref | urn:biopax:RelationshipXref... | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:xref | http://www.reactome.org/bio... | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:xref | urn:biopax:UnificationXref:... | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:xref | urn:biopax:UnificationXref:... | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:dataSource | urn:biopax:Provenance:react... | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:dataSource | http://www.reactome.org/bio... | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:displayName | Amino Acid conjugation | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:organism | http://identifiers.org/taxo... | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:pathwayComponent | http://www.reactome.org/bio... | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:pathwayOrder | http://www.reactome.org/bio... | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:stepProcess | http://www.reactome.org/bio... | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:pathwayComponent | http://www.reactome.org/bio... | lld:biopax3 |
