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rdf:type |
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calbc:hasCorrelation |
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skos:exactMatch |
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skos:definition |
MSH: A thioester hydrolase which acts on esters formed between thiols such as DITHIOTHREITOL or GLUTATHIONE and the C-terminal glycine residue of UBIQUITIN.,NCI: The Ubiquitin C-Terminal Hydrolases (UCH) are deubiquitinating enzymes which hydrolyze carboxyl-terminal esters and amides of ubiquitin to generate free monomeric ubiquitin from ubiquitin proproteins, but not to deubiquitinate ubiquitin-protein conjugates or disassemble polyubiquitin chains. The expression of these enzymes is tissue-specific and developmentally regulated. Members of this deubiquitinating family are also important modulators of cellular function. (NCI)
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skos:inScheme |
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skos:narrower |
umls-concept:C0662611,
umls-concept:C0911619,
umls-concept:C0912263,
umls-concept:C0914618,
umls-concept:C0967992,
umls-concept:C1100344,
umls-concept:C1121091,
umls-concept:C1142946,
umls-concept:C1172633,
umls-concept:C1175888,
umls-concept:C1310740,
umls-concept:C1431818,
umls-concept:C1432495,
umls-concept:C1434943,
umls-concept:C1435231,
umls-concept:C1435778,
umls-concept:C1436157,
umls-concept:C1436430,
umls-concept:C1438539,
umls-concept:C1447339,
umls-concept:C1447340,
umls-concept:C1448199,
umls-concept:C1450120,
umls-concept:C1450330,
umls-concept:C1505881,
umls-concept:C1566220,
umls-concept:C1569904,
umls-concept:C1665663,
umls-concept:C1681239,
umls-concept:C1698205,
umls-concept:C1742198,
umls-concept:C1743421,
umls-concept:C1869353,
umls-concept:C2001097,
umls-concept:C2351756,
umls-concept:C2713563,
umls-concept:C2974960,
umls-concept:C2976211,
umls-concept:C3180912,
umls-concept:C3492052,
umls-concept:C3493568
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skos-xl:prefLabel |
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skos-xl:altLabel |
umls-label:A17882296,
umls-label:A17906451,
umls-label:A17978840,
umls-label:A18026252,
umls-label:A18050500,
umls-label:A18050501,
umls-label:A2786458,
umls-label:A2786459,
umls-label:A2786689,
umls-label:A2787568,
umls-label:A2787569,
umls-label:A2788380,
umls-label:A2788381,
umls-label:A2791361,
umls-label:A2791362,
umls-label:A2791363,
umls-label:A2791364,
umls-label:A2791365,
umls-label:A2791366,
umls-label:A2791367,
umls-label:A2794157,
umls-label:A2794643,
umls-label:A2794644,
umls-label:A2795591,
umls-label:A7589582,
umls-label:A7628145
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umls:relation |
http://linkedlifedata.com/resource/umls/relation/R119412453,
http://linkedlifedata.com/resource/umls/relation/R28480030,
http://linkedlifedata.com/resource/umls/relation/R28480031,
http://linkedlifedata.com/resource/umls/relation/R28480055,
http://linkedlifedata.com/resource/umls/relation/R28480385,
http://linkedlifedata.com/resource/umls/relation/R28480386,
http://linkedlifedata.com/resource/umls/relation/R28480640,
http://linkedlifedata.com/resource/umls/relation/R28480641,
http://linkedlifedata.com/resource/umls/relation/R28481570,
http://linkedlifedata.com/resource/umls/relation/R28481571,
http://linkedlifedata.com/resource/umls/relation/R28554844,
http://linkedlifedata.com/resource/umls/relation/R28554845,
http://linkedlifedata.com/resource/umls/relation/R28554846,
http://linkedlifedata.com/resource/umls/relation/R28481572,
http://linkedlifedata.com/resource/umls/relation/R28481573,
http://linkedlifedata.com/resource/umls/relation/R28554847,
http://linkedlifedata.com/resource/umls/relation/R28554848,
http://linkedlifedata.com/resource/umls/relation/R28554849,
http://linkedlifedata.com/resource/umls/relation/R28554850
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