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skos:definition |
NCI: Expressed in germ cells in the testis by human BRS3 Gene (GPCR1 Family), 399-aa 44-kDa integral membrane protein Bombesin-like Receptor 3 is specifically activated by bombesin-like peptides and associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. Bombesin-like peptide receptors include gastrin-releasing peptide receptor, neuromedin B receptor, and bombesin receptor subtype-3 (BRS3). BRS3 may be required for sperm cell division, maturation, or function, or for regulation of endocrine processes and metabolism responsible for energy balance and adiposity. (NCI)
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