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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1998-12-2
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pubmed:abstractText |
We studied genetic polymorphisms in the tumor necrosis factor (TNF) region in 81 Japanese patients with Guillain-Barré syndrome (GBS) and 85 controls. A significantly higher frequency of the 100-base pair (bp) (TNFa2) allele of the TNFa microsatellite marker, which is associated with high TNF alpha production, existed in Campylobacter jejuni-positive (Cj+) GBS patients than in controls, suggesting the involvement of a genetic predisposition to high TNF alpha secretion in the development of C. jejuni-related GBS.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0364-5134
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
44
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
815-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9818939-Alleles,
pubmed-meshheading:9818939-Campylobacter Infections,
pubmed-meshheading:9818939-Campylobacter jejuni,
pubmed-meshheading:9818939-DNA Primers,
pubmed-meshheading:9818939-Humans,
pubmed-meshheading:9818939-Japan,
pubmed-meshheading:9818939-Microsatellite Repeats,
pubmed-meshheading:9818939-Polymerase Chain Reaction,
pubmed-meshheading:9818939-Polymorphism, Genetic,
pubmed-meshheading:9818939-Polyradiculoneuropathy,
pubmed-meshheading:9818939-Reference Values,
pubmed-meshheading:9818939-Tumor Necrosis Factor-alpha
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pubmed:year |
1998
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pubmed:articleTitle |
Genetic contribution of the tumor necrosis factor region in Guillain-Barré syndrome.
|
pubmed:affiliation |
Department of Neurology and Clinical Research Center, Utano National Hospital, Kyoto, Japan.
|
pubmed:publicationType |
Journal Article,
Comparative Study
|