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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
1998-11-30
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pubmed:abstractText |
Tumor necrosis factor (TNF)-alpha causes much of the hepatocellular injury and cell death that follows toxin-induced liver damage. The mechanism by which toxic liver injury sensitizes hepatocytes to TNF-alpha cytotoxicity is unknown. The aim of this study was to determine the role of the antioxidant glutathione in this process.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0016-5085
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
115
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1229-37
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:9797379-Animals,
pubmed-meshheading:9797379-Cells, Cultured,
pubmed-meshheading:9797379-Dactinomycin,
pubmed-meshheading:9797379-Drug Combinations,
pubmed-meshheading:9797379-Galactosamine,
pubmed-meshheading:9797379-Glutathione,
pubmed-meshheading:9797379-Immunity, Innate,
pubmed-meshheading:9797379-Lipopolysaccharides,
pubmed-meshheading:9797379-Liver,
pubmed-meshheading:9797379-Male,
pubmed-meshheading:9797379-Mice,
pubmed-meshheading:9797379-Mice, Inbred Strains,
pubmed-meshheading:9797379-Rats,
pubmed-meshheading:9797379-Rats, Sprague-Dawley,
pubmed-meshheading:9797379-Tumor Necrosis Factor-alpha
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pubmed:year |
1998
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pubmed:articleTitle |
Glutathione modulates rat and mouse hepatocyte sensitivity to tumor necrosis factor toxicity.
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pubmed:affiliation |
Department of Medicine and the Marion Bessin Liver Research Center, Albert Einstein College of Medicine, Bronx, NY, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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