| pubmed-article:9792813 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9792813 | lifeskim:mentions | umls-concept:C0022567 | lld:lifeskim |
| pubmed-article:9792813 | lifeskim:mentions | umls-concept:C1510411 | lld:lifeskim |
| pubmed-article:9792813 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
| pubmed-article:9792813 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
| pubmed-article:9792813 | lifeskim:mentions | umls-concept:C1456820 | lld:lifeskim |
| pubmed-article:9792813 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:9792813 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:9792813 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:9792813 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:9792813 | pubmed:dateCreated | 1998-11-23 | lld:pubmed |
| pubmed-article:9792813 | pubmed:abstractText | The 37 LRP/p40 molecule is a bi-functional protein in which expression is increased in a large variety of cancers in association with their metastatic phenotype. Here we present the first data concerning the 37 LRP/p40 gene promoter activity and show that it is very active in a cervix carcinoma cell line. Interestingly, despite hallmarks of a housekeeping gene, we show that the 37 LRP/p40 gene promoter can be down-regulated by two potentially anticancerous cytokines, TNF-alpha and IFN-gamma. In addition, the dual fate of the protein, i.e., being intracellularly involved in the cell translation machinery and incorporated into a 67-kDa cell surface protein functioning as a laminin receptor (67LR), is differentially affected by the treatment. Our data suggest multiple regulation levels in the control of the 67LR/37LRP/p40 molecule expression and uncover new clues for the understanding of both the control of expression of this metastasis-associated molecule and the IFN-gamma and TNF-alpha anticancerous action. | lld:pubmed |
| pubmed-article:9792813 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9792813 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9792813 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9792813 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9792813 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9792813 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9792813 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9792813 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9792813 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9792813 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9792813 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9792813 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9792813 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9792813 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:9792813 | pubmed:issn | 0006-291X | lld:pubmed |
| pubmed-article:9792813 | pubmed:author | pubmed-author:JacobiPP | lld:pubmed |
| pubmed-article:9792813 | pubmed:author | pubmed-author:DelvennePP | lld:pubmed |
| pubmed-article:9792813 | pubmed:author | pubmed-author:JackersPP | lld:pubmed |
| pubmed-article:9792813 | pubmed:author | pubmed-author:CastronovoVV | lld:pubmed |
| pubmed-article:9792813 | pubmed:author | pubmed-author:van den... | lld:pubmed |
| pubmed-article:9792813 | pubmed:author | pubmed-author:ClausseNN | lld:pubmed |
| pubmed-article:9792813 | pubmed:author | pubmed-author:Franzen-Detro... | lld:pubmed |
| pubmed-article:9792813 | pubmed:copyrightInfo | Copyright 1998 Academic Press. | lld:pubmed |
| pubmed-article:9792813 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9792813 | pubmed:day | 20 | lld:pubmed |
| pubmed-article:9792813 | pubmed:volume | 251 | lld:pubmed |
| pubmed-article:9792813 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9792813 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9792813 | pubmed:pagination | 564-9 | lld:pubmed |
| pubmed-article:9792813 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
| pubmed-article:9792813 | pubmed:meshHeading | pubmed-meshheading:9792813-... | lld:pubmed |
| pubmed-article:9792813 | pubmed:meshHeading | pubmed-meshheading:9792813-... | lld:pubmed |
| pubmed-article:9792813 | pubmed:meshHeading | pubmed-meshheading:9792813-... | lld:pubmed |
| pubmed-article:9792813 | pubmed:meshHeading | pubmed-meshheading:9792813-... | lld:pubmed |
| pubmed-article:9792813 | pubmed:meshHeading | pubmed-meshheading:9792813-... | lld:pubmed |
| pubmed-article:9792813 | pubmed:meshHeading | pubmed-meshheading:9792813-... | lld:pubmed |
| pubmed-article:9792813 | pubmed:meshHeading | pubmed-meshheading:9792813-... | lld:pubmed |
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| pubmed-article:9792813 | pubmed:meshHeading | pubmed-meshheading:9792813-... | lld:pubmed |
| pubmed-article:9792813 | pubmed:meshHeading | pubmed-meshheading:9792813-... | lld:pubmed |
| pubmed-article:9792813 | pubmed:meshHeading | pubmed-meshheading:9792813-... | lld:pubmed |
| pubmed-article:9792813 | pubmed:meshHeading | pubmed-meshheading:9792813-... | lld:pubmed |
| pubmed-article:9792813 | pubmed:meshHeading | pubmed-meshheading:9792813-... | lld:pubmed |
| pubmed-article:9792813 | pubmed:meshHeading | pubmed-meshheading:9792813-... | lld:pubmed |
| pubmed-article:9792813 | pubmed:meshHeading | pubmed-meshheading:9792813-... | lld:pubmed |
| pubmed-article:9792813 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9792813 | pubmed:articleTitle | TNF-alpha and IFN-gamma down-regulate the expression of the metastasis-associated bi-functional 37LRP/p40 gene and protein in transformed keratinocytes. | lld:pubmed |
| pubmed-article:9792813 | pubmed:affiliation | Metastasis Research Laboratory, Sart Tilman, Liège, B-4000, Belgium. | lld:pubmed |
| pubmed-article:9792813 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9792813 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9792813 | lld:pubmed |
