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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
1998-11-24
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pubmed:abstractText |
Twelve consecutive children with high-risk leukemia have been submitted to UCB transplant from unrelated 1 or 2 loci HLA-mismatched donor. All patients received an identical regimen for conditioning and GVHD prophylaxis. The median dose of viable nucleated cells infused was 2.8 x 10(7)/kg bw (range 1.4-7.9). Of 11 patients evaluable for engraftment, the hematopoiesis was of full donor origin in seven patients and autologous in four. The probability of disease-free survival at 1 and 2 years from UCB transplant is 60 and 42%, respectively.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0268-3369
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pubmed:author |
pubmed-author:ArceseWW,
pubmed-author:BoecklinFF,
pubmed-author:CarminiDD,
pubmed-author:ChaeE UEU,
pubmed-author:CiminoGG,
pubmed-author:De FeliceLL,
pubmed-author:GuglielmiCC,
pubmed-author:IoriA PAP,
pubmed-author:LaurentiLL,
pubmed-author:MandelliFF,
pubmed-author:MengarelliAA,
pubmed-author:MoletiM LML,
pubmed-author:PerronePP,
pubmed-author:RomanoAA,
pubmed-author:ScrenciMM,
pubmed-author:TestiA MAM
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pubmed:issnType |
Print
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pubmed:volume |
21 Suppl 3
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
S85-6
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9712504-Adolescent,
pubmed-meshheading:9712504-Child,
pubmed-meshheading:9712504-Child, Preschool,
pubmed-meshheading:9712504-Disease-Free Survival,
pubmed-meshheading:9712504-Female,
pubmed-meshheading:9712504-Fetal Blood,
pubmed-meshheading:9712504-Fetal Tissue Transplantation,
pubmed-meshheading:9712504-Hematopoietic Stem Cell Transplantation,
pubmed-meshheading:9712504-Histocompatibility Testing,
pubmed-meshheading:9712504-Humans,
pubmed-meshheading:9712504-Leukemia,
pubmed-meshheading:9712504-Male,
pubmed-meshheading:9712504-Transplantation, Homologous,
pubmed-meshheading:9712504-Treatment Outcome
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pubmed:year |
1998
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pubmed:articleTitle |
Umbilical cord blood transplant from HLA-mismatched unrelated donor in high-risk leukemia.
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pubmed:affiliation |
Dipartimento di Biotecnologie Cellulari ed Ematologia, University La Sapienza, Rome, Italy.
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pubmed:publicationType |
Journal Article
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