9537488

Source:http://linkedlifedata.com/resource/pubmed/id/9537488

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0001554, umls-concept:C0021270, umls-concept:C0035236, umls-concept:C0205419, umls-concept:C0701159, umls-concept:C1257890, umls-concept:C1273870, umls-concept:C1512888, umls-concept:C2603343
pubmed:issue	3
pubmed:dateCreated	1998-6-5
pubmed:abstractText	Respiratory syncytial virus (RSV) is a frequent cause of hospitalization among infants. To compare patient management in Europe, the United States, and Australia, we analyzed the charts of 1,563 pediatric patients hospitalized with laboratory-confirmed RSV lower respiratory infections during recent RSV seasons. Half of patients had been seen initially as outpatients. Median duration of hospitalization was 4 days in Australia, Finland, the United Kingdom, and the United States, and 8 or 9 days in Belgium, France, Germany, Italy, and the Netherlands. In a linear regression model that included clinical findings, underlying conditions, prematurity, and age, the leading variable associated with length of stay was "hospitalization in continental Europe". This geographic factor conferred a 1.8-fold longer stay (95% CI: 1.7-1.9) than hospitalization elsewhere. Utilization of nine supportive therapies for RSV varied widely among hospitals, even within the same country. The individual hospital was strongly associated with the use of every therapy studied, independent of patient characteristics and clinical status. CONCLUSION: Management of RSV patients varies markedly by country and hospital. Multicenter RSV trials that measure length of stay should standardize criteria for "readiness for discharge". It may be appropriate to limit international trials to countries with similar median stays for RSV. Variability within multicenter trials could be further controlled by standardizing the use of other therapies and the diagnosis of complications.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/7603873
pubmed:citationSubset	IM
pubmed:status	MEDLINE
pubmed:month	Mar
pubmed:issn	0340-6199
pubmed:author	pubmed-author:BehrendtC ECE, pubmed-author:BurchD JDJ, pubmed-author:DeckerM DMD, pubmed-author:WatsonP HPH
pubmed:issnType	Print
pubmed:volume	157
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	215-20
pubmed:dateRevised	2006-11-15
pubmed:meshHeading	pubmed-meshheading:9537488-Ambulatory Care, pubmed-meshheading:9537488-Australia, pubmed-meshheading:9537488-Child, Preschool, pubmed-meshheading:9537488-Chronic Disease, pubmed-meshheading:9537488-Europe, pubmed-meshheading:9537488-Female, pubmed-meshheading:9537488-Hospitalization, pubmed-meshheading:9537488-Humans, pubmed-meshheading:9537488-Infant, pubmed-meshheading:9537488-Infant, Newborn, pubmed-meshheading:9537488-Length of Stay, pubmed-meshheading:9537488-Linear Models, pubmed-meshheading:9537488-Male, pubmed-meshheading:9537488-Multivariate Analysis, pubmed-meshheading:9537488-Respiratory Syncytial Virus Infections, pubmed-meshheading:9537488-Respiratory Tract Infections, pubmed-meshheading:9537488-Retrospective Studies, pubmed-meshheading:9537488-Risk Factors, pubmed-meshheading:9537488-Survival Rate, pubmed-meshheading:9537488-United States
pubmed:year	1998
pubmed:articleTitle	International variation in the management of infants hospitalized with respiratory syncytial virus. International RSV Study Group.
pubmed:affiliation	Epidemiology, SmithKline Beecham Pharmaceuticals, Collegeville, Pennsylvania 19426, USA.
pubmed:publicationType	Journal Article, Comparative Study