9531364

Source:http://linkedlifedata.com/resource/pubmed/id/9531364

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0015385, umls-concept:C0015967, umls-concept:C0025241, umls-concept:C0087111, umls-concept:C0205101, umls-concept:C0205179, umls-concept:C0396670, umls-concept:C1261473, umls-concept:C1456820, umls-concept:C1517927, umls-concept:C1522449, umls-concept:C2347880
pubmed:issue	4
pubmed:dateCreated	1998-4-8
pubmed:abstractText	Hyperthermic isolated limb perfusion (HILP) with tumor necrosis factor-alpha (TNF-alpha), interferon-gamma (IFN-gamma), and melphalan is associated with a dramatic antitumor effect in locally advanced extremity soft-tissue sarcomas (STS). The aim of this study was to demonstrate the feasibility and efficacy of adjuvant radiotherapy after HILP with TNF-alpha, IFN-gamma, and melphalan and delayed surgical resection.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/7603616
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Interferon-gamma, http://linkedlifedata.com/resource/pubmed/chemical/Melphalan, http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha
pubmed:status	MEDLINE
pubmed:month	Mar
pubmed:issn	0360-3016
pubmed:author	pubmed-author:HoekstraH JHJ, pubmed-author:MolenaarW MWM, pubmed-author:OliemanA FAF, pubmed-author:PratDD, pubmed-author:Schraffordt KoopsHH, pubmed-author:van GinkelR JRJ
pubmed:issnType	Print
pubmed:day	1
pubmed:volume	40
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	807-14
pubmed:dateRevised	2008-11-21
pubmed:meshHeading	pubmed-meshheading:9531364-Adolescent, pubmed-meshheading:9531364-Adult, pubmed-meshheading:9531364-Aged, pubmed-meshheading:9531364-Aged, 80 and over, pubmed-meshheading:9531364-Amputation, pubmed-meshheading:9531364-Antineoplastic Combined Chemotherapy Protocols, pubmed-meshheading:9531364-Chemotherapy, Cancer, Regional Perfusion, pubmed-meshheading:9531364-Combined Modality Therapy, pubmed-meshheading:9531364-Extremities, pubmed-meshheading:9531364-Feasibility Studies, pubmed-meshheading:9531364-Female, pubmed-meshheading:9531364-Follow-Up Studies, pubmed-meshheading:9531364-Humans, pubmed-meshheading:9531364-Hyperthermia, Induced, pubmed-meshheading:9531364-Interferon-gamma, pubmed-meshheading:9531364-Male, pubmed-meshheading:9531364-Melphalan, pubmed-meshheading:9531364-Middle Aged, pubmed-meshheading:9531364-Neoplasm Recurrence, Local, pubmed-meshheading:9531364-Radiotherapy, Adjuvant, pubmed-meshheading:9531364-Sarcoma, pubmed-meshheading:9531364-Tumor Necrosis Factor-alpha
pubmed:year	1998
pubmed:articleTitle	Feasibility and efficacy of external beam radiotherapy after hyperthermic isolated limb perfusion with TNF-alpha and melphalan for limb-saving treatment in locally advanced extremity soft-tissue sarcoma.
pubmed:affiliation	Department of Surgical Oncology, Groningen University Hospital, The Netherlands.
pubmed:publicationType	Journal Article