Linked Life Data

9388784

Source:http://linkedlifedata.com/resource/pubmed/id/9388784

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1997-12-22
pubmed:abstractText
Recent studies have defined a new Drosophila Jun amino-terminal kinase (DJNK) pathway. The first role that has been uncovered for this pathway is the control of cell differentiation and morphogenesis during the process of dorsal closure. This phosphorylation cascade has been conserved during evolution and several reports suggest that it becomes activated in response to the action of small GTPases. DJNK signalling impinges on transcription factors as DJun and Anterior open and eventually controls the expression of target genes such as decapentaplegic and puckered. Important progress has been made in the study of the coordination of DJNK and Decapentaplegic signalling during dorsal closure and their role in the control of cell shape changes--and possibly cell polarity--by promoting cytoskeletal changes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0959-437X
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
666-71
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Regulation of cell differentiation by the Drosophila Jun kinase cascade.
pubmed:affiliation
Department of Zoology, University of Cambridge, UK. em10008@cus.cam.ac.uk
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't