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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5343
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pubmed:dateCreated |
1997-12-18
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pubmed:abstractText |
Transgenic Drosophila that expressed either luciferase or green fluorescent protein driven from the promoter of the clock gene period were used to monitor the circadian clock in explanted head, thorax, and abdominal tissues. The tissues (including sensory bristles in the leg and wing) showed rhythmic bioluminescence, and the rhythms could be reset by light. The photoreceptive properties of the explanted tissues indicate that unidentified photoreceptors are likely to contribute to photic signal transduction to the clock. These results show that autonomous circadian oscillators are present throughout the body, and they suggest that individual cells in Drosophila are capable of supporting their own independent clocks.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Drosophila Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Green Fluorescent Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Luciferases,
http://linkedlifedata.com/resource/pubmed/chemical/Luminescent Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Nuclear Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/PER protein, Drosophila,
http://linkedlifedata.com/resource/pubmed/chemical/Period Circadian Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Cell Surface,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Fusion Proteins
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0036-8075
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
28
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pubmed:volume |
278
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1632-5
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:9374465-Animals,
pubmed-meshheading:9374465-Animals, Genetically Modified,
pubmed-meshheading:9374465-Biological Clocks,
pubmed-meshheading:9374465-Brain,
pubmed-meshheading:9374465-Chemoreceptor Cells,
pubmed-meshheading:9374465-Circadian Rhythm,
pubmed-meshheading:9374465-Darkness,
pubmed-meshheading:9374465-Drosophila,
pubmed-meshheading:9374465-Drosophila Proteins,
pubmed-meshheading:9374465-Gene Expression Regulation,
pubmed-meshheading:9374465-Genes, Insect,
pubmed-meshheading:9374465-Green Fluorescent Proteins,
pubmed-meshheading:9374465-Light,
pubmed-meshheading:9374465-Light Signal Transduction,
pubmed-meshheading:9374465-Luciferases,
pubmed-meshheading:9374465-Luminescence,
pubmed-meshheading:9374465-Luminescent Proteins,
pubmed-meshheading:9374465-Nuclear Proteins,
pubmed-meshheading:9374465-Period Circadian Proteins,
pubmed-meshheading:9374465-Photoreceptor Cells, Invertebrate,
pubmed-meshheading:9374465-Promoter Regions, Genetic,
pubmed-meshheading:9374465-Receptors, Cell Surface,
pubmed-meshheading:9374465-Recombinant Fusion Proteins
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pubmed:year |
1997
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pubmed:articleTitle |
Independent photoreceptive circadian clocks throughout Drosophila.
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pubmed:affiliation |
Department of Cell Biology and National Science Foundation Center for Biological Timing, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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