Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
|
pubmed:dateCreated |
1997-10-21
|
pubmed:abstractText |
The central player in the replication of RNA viruses is the viral RNA-dependent RNA polymerase. The 53 kDa poliovirus polymerase, together with other viral and possibly host proteins, carries out viral RNA replication in the host cell cytoplasm. RNA-dependent RNA polymerases comprise a distinct category of polymerases that have limited sequence similarity to reverse transcriptases (RNA-dependent DNA polymerases) and perhaps also to DNA-dependent polymerases. Previously reported structures of RNA-dependent DNA polymerases, DNA-dependent DNA polymerases and a DNA-dependent RNA polymerase show that structural and evolutionary relationships exist between the different polymerase categories.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0969-2126
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
5
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1109-22
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:9309225-Amino Acid Sequence,
pubmed-meshheading:9309225-Conserved Sequence,
pubmed-meshheading:9309225-Crystallography, X-Ray,
pubmed-meshheading:9309225-Molecular Sequence Data,
pubmed-meshheading:9309225-Poliovirus,
pubmed-meshheading:9309225-Protein Conformation,
pubmed-meshheading:9309225-Protein Structure, Secondary,
pubmed-meshheading:9309225-Protein Structure, Tertiary,
pubmed-meshheading:9309225-RNA Replicase
|
pubmed:year |
1997
|
pubmed:articleTitle |
Structure of the RNA-dependent RNA polymerase of poliovirus.
|
pubmed:affiliation |
Department of Chemistry and Biochemistry, University of Colorado, Boulder 80309, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|